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In addition, the complement of enzymes may be integrated into highly efficient complexes called cellulosomes (produced by anaerobic bacteria) that are composed of numerous functional protein modules which interact with each other (via cohesin-dockerin interactions) and with the substrate (via carbohydrate-binding modules), in order to synergistically degrade lignocellulosic biomass.
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Recently, 36 SOM proteins were extracted and identified from A. millepora skeleton, suggesting roles for numerous functional proteins in biomineralization, including ECM-cell adhesion proteins, enzymes, acidic proteins, and a toxin [ 127].
The most numerous functional categories included proteins involved in protein fate (164), metabolism (140), protein synthesis (101), cell rescue, defence and virulence (99) and cellular transport (97).
It is well known that osmolytes induce protein folding due to solvophobic effects on peptide backbone, and the fact that protein backbone comprises the most numerous functional groups of proteins, osmolyte-induced conformations result in native-like functional species [21].
All this peculiar structural organization seems to explain well the different numerous functional activities exerted by this protein [ 21].
The MBD proteins have numerous functional roles, including both transcriptional suppression and activation, as well as roles in nuclear organization, x-inactivation and splicing [ 13].
Proteins also perform numerous functional roles in the body.
Many multifunctional proteins are justifiably included in numerous functional categories.
SH performed numerous functional experiments and observed cyclin D1, p-Src proteins modulated after knocking down AGR2 in breast cancer cells.
These vast non-protein coding genomic areas, previously frequently referred to as "junk" DNA, contain numerous functional signals of various origin and purpose.
Being a large protein with 1636 amino acids and several putative structural domains it is likely that it can interact with numerous functional partners.
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