Sentence examples for numerous effector molecules from inspiring English sources
Inflammatory signals are generally initiated by the activation of multiple cell-surface receptors, then a limited number of kinase-signaling molecules, followed by numerous effector molecules [ 16- 18].
On the one hand, the combinatorial variety of nucleic acid strands allows for the numerous different effector molecules and accordingly facilitates the independent parallel operation of several allosterically controlled ribozymes.
This results in signal transduction through G proteins and a cascade of numerous downstream effector molecules that results in directed cell migration.
The importance of TWEAK on synovial pathophysiology was illustrated by the inhibition of TWEAK, which resulted in downregulation of numerous proinflammatory effector molecules such as the chemokines MIP-1β (CCL-4), lymphotactin (XCL-1), CXCL-10, MCP-1 (CCL-2) and RANTES (CCL-5) in articular mesenchymal cells, including fibroblasts [ 31].
The ability to engineer Group I introns to be responsive to effector molecules has numerous potential applications.
Small G-proteins belonging to the Arf (ADP-ribosylation factor) family serve as regulatory proteins for numerous cellular processes through GTP-dependent recruitment of effector molecules.
Activated T lymphocytes can be classified according to their production of specific effector molecules.
Both TSCM and TMNP cells, which express naive T cell markers (CD45RA+CD45RO−CCR7+CD62L+), respond rapidly to antigens, express multiple effector molecules and produce memory and effector cells.
Kaur, N. et al. T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules.
Oncogenic KRAS can activate numerous effector pathways to drive malignant progression.
Successful pathogens use effector molecules, encoded by Avr genes, not only to suppress host immunity but also to manipulate host cellular mechanisms for their own benefit, leading to effector-triggered susceptibility (ETS 28.
