Sentence examples for numerous drug interactions from inspiring English sources

Methadone has a complex pharmacokinetic profile marked by substantial interindividual pharmacokinetic variability and is associated with numerous drug interactions [3].

More recently, Nova designed a meter used in hospitals that corrects for numerous drug interactions that can throw off the results.

However, nephrotoxicity, hypertension, and numerous drug interactions may limit its use.

Care must be taken when prescribing cyclosporine, because of concerns about nephrotoxicity, hypertension, and numerous drug interactions.

However, the use of this alkaloid is often limited due to concerns regarding dose-related adverse effects, numerous drug interactions, and a narrow therapeutic index.

However, PI-based regimens require strict adherence to ensure efficacy, and many of these regimens incur a high pill burden, complex dosing schedules, numerous drug interactions, and metabolic complications including lipodystrophy, hyperlipidemia, and elevated glucose levels.

5 Data obtained from numerous drug-interaction studies testing nevirapine IR against other antiretroviral drugs, antibiotics, antifungals, antacids, contraceptives, drugs of addiction, and St John's Wort show potential interactions with compounds that are substrates for CYP3A and CYP2B6.

6, 7 Voriconazole has numerous drug-drug interactions, which may limit its usefulness in certain populations.

Numerous drug-drug interactions involving CIM have been identified, in most cases, due to inhibition of hepatic drug metabolism by CIM occurring at very low serum concentrations (Chang et al, 1992b).

However, boceprevir and telaprevir are associated with serious side effects, including rash and anemia, carry a high pill burden, require dosing every 8 h, and have numerous drug-drug interactions (3 – 7).

36 Because many drugs inhibit CYP3A4, and the enzyme activity differs significantly between individuals, numerous pharmacokinetic drug interactions are possible with fentanyl.