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It is difficult to attribute particular side effects to isolated drugs as combination drug therapy is the standard of care in this disease area and since numerous drug classes share common side effects.
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The numerous active drug classes in ovarian cancer mean that many sequential chemotherapy regimens are possible.
Oncology is therefore characterized by a growing number of older and medically unfit patients that receive numerous novel drug classes with unexpected side effects.
Generalized anxiety disorder (GAD), a disorder characterized by pervasive and highly distressing worries, is associated with impairment that is comparable to major depressive disorder (MDD). 1 Although numerous agents from various drug classes are available to treat GAD, as many as 50% of patients have inadequate response, 2 constituting a considerable unmet medical need.
CVD is the leading cause of death globally [ 6], and associated polypharmacy is common, driven by numerous evidence-based guidelines advocating treatment with multiple therapeutic drug classes [ 7- 9].
Patients on combination therapy were 4.5% more numerous than patients on monotherapy, and the most frequently used drug classes were calcium channel blockers, ACE inhibitors and diuretics.
Numerous clinical PK studies have demonstrated the influence of compromised renal clearance on plasma and tissue concentrations of various drug classes following renal disease.
Months of undercover investigation focused on dozens of drug dealers, as concealed cameras recorded numerous drug transactions.
Other drug classes such as histamine and adrenergic agents and 5-alpha reductase and aromatase inhibitors are linked to multiple disorder classes affecting the same organ system, such as numerous eye disorders and various endocrine disorders, respectively.
*Susceptible to all drug classes.
Protecting new drug classes is equally important.
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CEO of Professional Science Editing for Scientists @ prosciediting.com