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As recent reports on the Human Genome Project have acknowledged, "gene splicing" in higher organisms can produce numerous different proteins from a single gene.
The cellular replicating machine, or "replisome," is composed of numerous different proteins.
Replication is a complex task, depending on numerous different proteins and nucleic acids that function together in what has been likened to a machine (Alberts 1984).
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Monoclonal antibody and Fc fusion protein drugs are complex heterogeneous mixtures of numerous different protein variants and modifications.
Most important of all the activity of proteins, their cellular localisation and interaction with other proteins are regulated by a multitude of posttranslational modifications, including phosphorylation, acetylation, and glycosylation, which may combine to create numerous different "protein species" or "proteoforms" from each gene.
Although secretory pathways are termed and classified with a small number of apparatuses in cells, numerous different types of proteins have been identified as major components for the construction of secretory pathways, including membrane traffic and protein secretion [ 14].
The genotoxic drug doxorubicin is known to induce an accumulation of p53-family proteins in numerous different cell types.
Numerous reports on different protein-misfolding diseases show that soluble oligomeric species populated by amyloidogenic proteins can be quite toxic to cells.
Researchers have isolated, refined and genetically cloned human FGF-2 to clarify numerous different biological activities of the protein.
This has meant in many cases that we have needed to first deconvolute the literature which describes these systems using numerous different names for the same protein or complex.
In this view of signalling pathways proteins common to numerous different signalling systems e.g. MYD88 in the TLR system, are generally viewed as more important than other components in ensuring a network's robustness to perturbation due to their high degree of connectivity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com