Exact(1)
H2O2 is a toxic byproduct of cell metabolism and H2O2 generation from a variety of cellular processes increases in response to numerous developmental signals and biotic and abiotic stimulants [ 24].
Similar(59)
Microarray analyses revealed that numerous developmental signaling pathways were affected by Hdac3-deficiency.
Osteoblast development requires the expression of several transcription factors (e.g. Runx2 [2], [2] and osterix [3]) and the coordinated activation of numerous developmental signaling pathways [4].
Receptor-like kinases (RLKs) have been implicated in numerous developmental signalling pathways in plant development.
Protein kinase C (PKC) is a key component of numerous developmental signalling pathways, and the conventional PKC SpPKC1 was previously shown to be one of a number of genes that are significantly underexpressed in SpRunt-1 morphant embryos [ 16].
Certain genes were altered in only a subset of the conditions, for example, up-regulation of numerous developmental pathway and signaling genes in response to hydrogen peroxide.
In the mammary gland, IGFs stimulate proliferation, differentiation, and survival during numerous developmental stages; IGF signaling is required for puberty-dependent ductal outgrowth, stimulates lobuloalveolar development during pregnancy, and is reduced or absent during apoptosis-driven involution.
Red ripe tomatoes are the result of numerous physiological changes controlled by hormonal and developmental signals, causing maturation or differentiation of various fruit tissues simultaneously.
These genes were chosen because they are components of the Wnt/β-catenin pathway, an important cell signaling pathway implicated in numerous developmental processes, including regeneration [ 18- 29].
Canonical WNT signalling is central to numerous developmental processes and variants discovered within members of this pathway have been implicated in multiple complex diseases such as familial adenomatous polyposis coli, colorectal and hepatocellular cancers, type 2 diabetes and schizophrenia [ 10- 14].
PDGF-stimulated PDGFRα signaling is implicated in numerous developmental processes, including oligodendrogenesis, lung alveogenesis, spermatogenesis, intestinal villi and hair follicle morphogenesis, somite patterning, palate formation, and embryonic development [73].
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