The emergence of medical devices, which monitor and collect data at high frequency, the availability of data in numerous databases and the increased utilization of the electronic patient data to support physicians' clinical decisions, demand a high speed of data processing.
The implementation of this approach can take advantage of the numerous databases and tools currently used in the interpretation of genetic variants generated by clinical genetic testing or ES/WGS clinical research.
A comprehensive search of numerous databases was carried out.
As data floods entail further publications, the manual curation and update of numerous databases, using information from the literature, within a realistic timeframe, is a sine qua non.
Following this validation, an electronic search of numerous databases from three relevant fields (healthcare, health law and politics and management) will first be conducted by the research assistant with the supervision of the principal investigator and close support from the two information scientists.
12 The literature search was conducted in numerous databases including PubMed, Science Direct, Web of Science, BIOSIS, Journal of Citation Reports, CAB direct, and Google Scholar.
This has led to the accumulation of enormous amount of data across numerous databases and in literature.
Out of the numerous databases available to predict the target gene, we chose four databases, namely PicTar, Targetscan, Tarbase and miRecords.
Numerous databases [31,55,56] have cataloged several thousands of MRE-SNPs, and identification of functional SNPs amid these MRE-SNPs associated with a complex trait like autism is extremely challenging.
