Sentence examples for numerous chromosomal changes from inspiring English sources

This diversity is the result of numerous chromosomal changes that have accumulated during the evolution of the gibbon lineage, a quite unique feature in comparison with other hominoids and most of the other primates.

The contribution of numerical chromosomal changes is more than that of chromosomal translocations.

Childhood leukemia is characterized by the presence of balanced chromosomal translocations or by other structural or numerical chromosomal changes.

BTL2 cells, derived from the first recurrence progressing during RT and chemotherapy, showed numerous additional chromosomal changes as compared to BTL1 (asterisks in Figure 1B).

In one case, the origin of six species of Taterillus gerbils within the past 0.4 million years has been accompanied by numerous large chromosomal changes and the non-random accumulation of LINE-1 elements, with the most recently diverged species showing the greatest amount of LINE-1 accumulation [ 18].

Although few studies have separately analyzed rectal cancer they indicate that approximately 80 to 98% of these cancers arise through the chromosomal instability pathway (CIN), presenting high mutational frequency in APC, TP53, and KRAS in addition to numerous chromosome changes [ 2, 3, 5].

OS is a pediatric bone tumor with characteristically high level of numerical and structural chromosomal changes.

An alternative hypothesis is that dramatic changes in chromosome number appear as a consequence of a within-species accumulation of numerous chromosomal rearrangements, resulting in highly polymorphic systems with the subsequent extinction of intermediate karyomorphs.

Gross chromosomal changes were defined as changes that involved an entire or almost entire chromosome.

They found no correlation between advanced age and the kinds of chromosomal changes that cause Down syndrome, but suggested that a small proportion of older fathers may be at increased risk for transmitting multiple genetic and chromosomal defects.

Two important principles dictate the properties of a large proportion of structural chromosomal changes.