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D) This mesenchymal tissue shows numerous cells with PCNA positive immunostaining.
Interestingly, we observed that MSL1- and MSL2-depleted differentiating cells contained numerous cells with two inactive X chromosomes.
As such, although most elderly individuals have numerous cells with the requisite mutations necessary for cancer initiation, the progression into invasive cancer is relatively rare.
On polystyrene surface, RSCs started to adopt fibroblast-like shape in early hours (day 1), and, at day 4, numerous cells with fibroblast-like shape could be observed.
A strong anisocytosis, numerous cells with multiple nuclei, anisokaryosis, multiple mitotic figures, to some extent atypical mitotic figures, and a varying nucleus: plasma ratio could be detected.
In agreement with the gene expression analysis, we detected numerous cells with a nuclear staining of p63 and Snail2 in HGF-treated spheres, whereas untreated cells were negative for these markers.
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Hemorrhage and trauma, like infection, are insults that induce an acute inflammatory response involving a coordinated mobilization of numerous cells and molecules, with repercussions on all organ systems [8], [9], [10], [11].
Here, we demonstrated that numerous cells double labeled with pVim/Nkx2.1 or Sox2/Nkx2.1 are apical radial glia progenitors proliferating on the VZ surface.
On the serosal surfaces of abdominal organs, activated mesothelial cells proliferated with numerous cells sloughing into the overlying fibrinous exudate within which there was much streaming basophilic material (presumed DNA from degenerating cells) and infiltrating leukocytes.
The polymerized fibronectin shows highly adhesive properties entering the interaction with numerous cells by integrin receptors and stimulates the migration and adhesion of fibroblasts, keratinocytes, and endothelial cells.
COXI immunolabelling showed mosaic COXI expression in cultures A C, with numerous cells exhibiting reduced COXI, unlike the homogenous expression of controls (Fig. 3Ba d).
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