Sentence examples for numerous cell cycles from inspiring English sources

This occurs due to alterations of a gene expression status of relevant genes in a specific cell type, which is then inherited through numerous cell cycles.

Unlike neural progenitor cells, however, BCPCs do not become postmitotic and differentiate in a controlled way, but continue to divide for numerous cell cycles and grow a tumor mass.

Quantitative RT-PCR analyses revealed significant changes in the expression of numerous cell cycle genes (Fig. 4 A ).

In our study, a decrease of expression levels occurred very early in response to T in numerous cell cycle genes.

It has been demonstrated that the depletion of polyamines can lead to cell cycle arrest or apoptosis by affecting numerous cell cycle regulatory pathways [ 34].

Numerous cell cycle genes have been identified with AhR activation such as PAI-1 and SOS (Huang and Elferink 2005 ; Pierre et al. 2011 ).

Continued studies of how NF-κB can directly regulate expression of numerous cell cycle related genes is warranted, given these findings.

These proteins are among numerous cell cycle regulators, including other cyclins, CDKs, CDK inhibitors and CDCs, that precisely control the mitotic cell cycle during the four cell phases and several checkpoints to accomplish DNA replication and subsequent division.

We have shown previously that adenoviral overexpression of FoxM1 is able to drive β-cell proliferation in mouse and human islet through upregulation of numerous cell cycle genes (10).

There was a significant reduction in the expression of numerous cell cycle genes from the late G1 phase through the M phase, and cells were arrested at the G1/S checkpoint.

Although SKP2 targets numerous cell cycle regulators for ubiquitination and degradation, the oncogenic potential of SKP2 is mainly linked to p27 degradation, as evidenced by low levels of p27 in aggressive tumors in which SKP2 expression is high.