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Numerous candidate gene association studies have been performed to date, focusing almost exclusively on genes encoding major cytokines.
Numerous candidate gene studies in economics investigate whether specific SNPs correlate with measures of economic primitives such as risk aversion and delay discounting parameters, thus providing its biological microfoundation.
Numerous candidate gene studies designed to identify PCOS susceptibility loci have been published, but most nominally significant positive findings have not been confirmed in follow-up replication studies (reviewed in [25], [26]).
Numerous candidate gene studies have been conducted for TB; though there is consistent support for a role of human genetics in disease risk, the results for specific genes have been equivocal (reviewed in [4]).
Numerous candidate gene studies have been performed for colorectal cancer, and a large number have detected associations.
Numerous candidate gene studies have failed to identify unambiguous associations (see Discussion section in Tan et al., 2004; Cavalleri et al., 2005, 2007).
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Meta-analysis of the three expert-rater-scored cohorts revealed six associated loci harboring numerous candidate genes, including EDAR, SP5, MRPS22, ADGRG6 (GPR126), KIAA1217, and PAX9.
Numerous candidate genes have been located, with only small effects attributable to any particular gene.
Thus, cDNA-AFLPs provide numerous candidate genes relatively quickly and inexpensively.
2, 7, 8 Numerous candidate genes have been linked with the 22q11DS phenotype.
The identification of numerous candidate genes in these studies highlights their value.
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