Grasping the mechanics of this has helped us develop drugs for numerous cancers, including leukemia and lung cancer.
Consumption of arsenic-contaminated drinking water is associated with numerous cancers and dermal and vascular diseases.
The transcription factor GATA3 has recently been found to be involved in the carcinogenesis for numerous cancers.
The dysfunction and upregulation of ACL in numerous cancers makes it an attractive target for developing anticancer therapies.
Their work has helped establish links between arsenic exposure and many chronic diseases, including numerous cancers, cardiovascular and respiratory diseases, diabetes and cognitive development delays in children.
In particular, BCL-2 family proteins are vital regulators of mitochondrial integrity and have been implicated in the development, maintenance and chemoresistance of numerous cancers.
Mason has studied numerous cancers including leukemia and brain tumors as well as unidentified diseases with the National Institutes of Health's Undiagnosed Disease Program.
Human carbonic anhydrase 9th isoform (CA IX) is an important marker of numerous cancers and is increasingly interesting as a potential anticancer drug target.
Oxazaphosphorines including cyclophosphamide, trofosfamide and ifosfamide (IFO) belong to the alkylating agent class and are indicated in the treatment of numerous cancers.
Dysregulated hedgehog (HH) signaling has been found in numerous cancers, suggesting that therapeutic targeting of this pathway may be useful versus a wide range of cancers.
Adoptive immunotherapy adopting chimeric antigen receptor (CAR) modified T cells has arisen attention as a hard-hitting therapy for numerous cancers.
