Exact(5)
The genome-wide examination of gene expression with this technology has provided transcript profiles of numerous biological samples.
Biomarker studies require processing and storage of numerous biological samples with the goals of obtaining a large amount of information and minimizing future research costs.
In epidemiological studies, obtaining numerous biological samples over time is atypical due to the high cost and excessive burden on study participants.
It is impossible to analyze a large data set from numerous biological samples with different traits along with their technical and biological replicates when only one RNA sample can be processed at a time.
From each animal we collected, at days 0 and 13, numerous biological samples: urine, to measure proteinuria by colorimetry; blood to determine VLA-4 expression by flow citometry; renal tissue to study the expression of VCAM-1 by Western blot, the presence of cellular infiltrates by immunohistochemistry, the IgG deposition by immunofluorescence, and the cytokines expression by RT-PCR.
Similar(55)
The advances of mass spectrometry techniques combined with bioinformatics allow detection, identification and quantification of numerous peptides and proteins in biological samples (e.g. [ 81- 86]).
We identified 42 cohort studies with a total of > 3.5 million enrolled women that have ascertained breast cancer incidence as an outcome measure and have collected biological samples, presenting numerous opportunities to apply novel exposure measures in breast cancer epidemiology.
Considering the importance of plasmalogen molecular species to cellular function, detailed investigations of ether lipid biosynthesis, remodeling, trafficking, and catabolism will depend heavily on the advances in lipidomics that facilitate increased identification, quantitation, and kinetics of the numerous plasmalogens molecular species present in biological samples.
Biological samples collected from Australian waters by numerous workers over a long period are held in many repositories.
Since IMS experiments directly subject tissue section samples that are complex mixtures of numerous biological molecules, mass spectra obtained by IMS comprised hundreds of peaks derived from biological molecules as well as matrix clusters.
Numerous studies were also devoted to determination of steroids in biological samples by HPLC coupled with various detection techniques [ 31– 31].
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