Sentence examples for numerous biological pathways from inspiring English sources
Although the mechanisms by which the Mediator complex regulates transcription are often complicated by the context-dependent regulation, this transcription cofactor complex plays a pivotal role in numerous biological pathways.
We found that these phenotypes could be rescued by intervening in numerous biological pathways, including IGF-1/insulin signaling, mitophagy, and the mitochondrial unfolded protein response, suggesting that it may be possible to ameliorate mtDNA disease through multiple molecular mechanisms.
Using this resource, it is possible to examine the occurrence and evolution of numerous biological pathways that organisms utilize.
Identification of the site-specific calpain substrates is fundamental for dissecting the roles of calpain cleavage in numerous biological pathways.
MicroRNAs (miRs) are important post-transcriptional regulators of gene expression that play crucial roles in numerous biological pathways.
The chosen compounds modulate numerous biological pathways and alter the functions of hundreds of different proteins, including many membrane proteins (Table 1 and Supporting Information Table S1).
Despite numerous studies, the exact biological pathways that give rise to these changes remains elusive.
Phenolic phytochemicals modulate numerous unrelated proteins and biological pathways but few binding sites have been identified.
Additionally, since a single miRNA can regulate numerous target mRNAs within biological pathways, modulation of a miRNA in principle allows for influencing an entire gene network and modifying complex disease phenotypes (van Rooij & Olson, 2012).
As Akt is a common downstream effector of many receptor tyrosine kinases, the finding that the Akt and Stat5 signaling pathways are functionally interconnected has important implications for the numerous biological processes regulated by these pathways.
Lipid signaling has a close relationship with the signaling pathways of numerous biological processes, such as inflammation, immunity, and glucose and amino acid metabolism [ 29- 32].
