Sentence examples for numerous binding partners from inspiring English sources
Since the discovery of DHCR24, numerous binding partners and cofactors have been identified and characterized.
This protein has several interaction sites with numerous binding partners, including α-actin [ 39].
Sla1 has numerous binding partners and regulatory interactions and the capacity to both positively and negatively regulate endocytosis.
The identification of numerous binding partners led to substantial progress in our understanding of the differential functions of Dia proteins.
Because of the numerous binding partners for CaM inside cells, it was expected that the mobility and distribution of eGFP-CaM would be complex.
This is illustrated by Figure 3, which represents a set of complexes of various p53 fragments or domains with numerous binding partners.
This does not eliminate the possibility that MSH2 heterodimerizes with any of its numerous other binding partners to accomplish nuclear import, but does demonstrate that MSH2 and MSH6 achieve nuclear localization independently and opens new avenues of investigation into their independent regulation.
Numerous IQGAP1 binding partners are known to be involved in tumorigenesis [ 22].
26 As full-length vinculin contains binding sites for numerous cellular binding partners regulating focal adhesions, cell cell junctions, and cell motility, 35 force-activation of vinculin may result in subsequent vinculin dependent cellular signaling.
Discovery of the numerous cellular binding partners of HR-E6 has allowed for the identification of two binding motifs or sequences which E6 preferably targets for interaction, the seven-residue leucine-containing motif, LxxϕLsh, and the PDZ domain.
Numerous additional binding partners of this complex function as either positive or negative regulators and include BAX-interacting factor-1 (BIF-1), ATG14L, UVRAG (UV irradiation resistance-associated gene), Ambra1 (activating molecule in Beclin-1-regulated autophagy protein 1), and Rubicon [ 23, 26, 29, 35, 36].
