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The outer membrane of Gram-negative bacteria forms an effective barrier to such molecules.[4] Consequently, numerous antibiotics that are active against Gram-positive organisms are much less active against Gram-negative bacteria.
The global spread of bacterial resistance to numerous antibiotics requires on going development of new drugs.
High G + C content genomes encompass the majority of actinobacteriaea, a distinct bacterial phylum capable of producing numerous antibiotics [ 16].
These findings are of great significance, especially in the case of S. aureus and B. cereus that are well-known for being resistant to numerous antibiotics.
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going development of new drugs to enter the market.
Microbiologic diagnosis can be difficult to obtain due to the organism's slow rate of growth and sensitivity to numerous antibiotics which are generally started early and empirically.
Similar(47)
Numerous antibiotic alternatives, such as pre- and probiotics, have been proposed but show variable success.
The multidrug resistance (MDR) in S. aureus is a complicated problem that is difficult to overcome due to the presence of numerous antibiotic resistance genes and it exhibit resistance to most of the currently available antibiotics.
Soil contains numerous antibiotic-producing species [7], which generate compounds with roles in killing competitors as well as in inter- and intra-species signaling [8].
These properties constitute a barrier to the penetration of numerous antibiotic molecules.
The elderly patients are particularly susceptible to various infections and exposed to numerous antibiotic and antifungal treatments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com