Sentence examples for numerous agents with from inspiring English sources

Numerous agents with multiple, nonoverlapping mechanisms of action have achieved US Food and Drug Administration FDAapprovalval for the indication of metastatic castrate-resistant prostate cancer (CRPC).

Numerous agents with different mechanisms of action and different pharmacological profiles are being used with the aim of improving glycemic control in patients with diabetes.

Because of the availability of numerous agents, patients with breast cancer may receive several different lines of treatment throughout the course of their disease.

It is anticipated that an agent based approach would consist of numerous agents imbued with attributes such as an individualised propensity for movement which would then react to features of the indoor environment and to their colleagues.

Progress has been frustratingly slow with numerous agents in combination with gemcitabine demonstrating promise in phase II studies, but minimal impact on OS in subsequent phase III randomised trials.

Numerous agents that interfere with DNA replication, transcription or other fundamental cellular processes are used to inhibit the growth of rapidly proliferating cancer cells and are among US Food and Drug Administration (FDA -approved cancer drugs.

Complexity science is the study of evolving, complex systems that are made up of many smaller interacting elements with numerous agents that operate independently but continuously affect each other.

Cholestatic hepatitis is a common form of drug-related injury and has been associated with numerous agents from almost all pharmacologic categories.

Because temsirolimus and its primary metabolite, sirolimus, are metabolised by the cytochrome P450 3A4 pathway (CYP3A4), the potential exists for pharmacokinetic (PK) drug interactions with the numerous agents that modulate CYP3A4 isozyme activity.

In contrast to the numerous agents developed to interact directly with the C5aR activation site located inside the receptor core (Proctor et al. 2006; Chen et al. 2010), CHIPS blocks activation by C5a by binding with high affinity to the flexible extra-cellular N-terminal portion of the C5aR (Postma et al. 2005).

An ABS consists of numerous agents, which follow localized rules to interact with a simulated environment, thereby formulating a bottom-up system.