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The frequent detection of HRV-C mono-infection in a substantial proportion of subjects presenting with LRTIs and URTIs (Fig. 4) is concordant with recent PCR-based studies [13] [17], [29], [33], [34] that demonstrate a numerically significant role for HRV-C and other rhinovirus species in severe respiratory disease requiring hospitalisation in children and exacerbation of asthma.
Numerically, the most substantial alterations were the change in the genus Bifidobacterium (e.g. Bifidobacterium adolescentis), which increased approximately 10 fold (from 2 3% to 18 30%) in three subjects through RS4.
There is a third cause that may be numerically very significant: definitional leap.
In mice treated with the gavage protocol for 17 days we observed a reduction in the bacterial DNA load that was substantial though numerically not as great as the reduction observed in cultivation assays.
Although the algorithm converges on roughly the same optimality score (it is numerically stable), there is substantial variation in parameter values.
We must state that the results, despite being numerically different, were similar from a substantial point of view.
The small size of the study decreases the statistical power to identify statically significant differences even though numerically the difference between the negative control group (inoculated with broth only) and the positive control group (M. haemolytica) were substantial.
Although numerically small (average 0.01), such differences can have a substantial effect on sample size, even when the average of cluster is small [ 15].
If there are non-substantial particulars, then Socrates' whiteness is a numerically distinct particular from Plato's whiteness.
Islam is numerically small but followed more passionately, at least by a substantial minority of its adherents; Muslims are quite sharply divided over how to interpret their faith.
Several attempts to numerically estimate the contribution of HGT to eukaryotic genomes suggest a substantial inter-taxon variation in the number of horizontally derived genes [ 7, 12, 52, 83, 84].
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