Wired is referring to the fact that a yottabyte is the largest storage term we have, not that septillion is the highest numerical descriptor for a large figure in existence, if you were confused.
The result of this geometrical atom-wise similarity calculation is integrated into the original RBF of the OAK in the form of an additional numerical descriptor.
To visualize similarities in behavior a Euclidian distance based similarity matrix of all 20 by 20 AAs was calculated and visualized in a heat map for each pair of numerical descriptor sets (12 sets).
The reason for this large difference is likely that the feature based descriptor set uses a single variable per amino acid, where the numerical descriptor sets use 3 (ProtFP (PCA3), Z-scales (3) and MS-WHIM) to 10 values (BLOSUM).
The significance and variance of the heme coordination urges the use of a numerical descriptor other than the binary, presence (1) or absence (0), for describing insignificant contributions (< 1 log unit) of hydrogen bonds and interactions with heme iron (FP1-FP7).
Each genome position is assigned to a number array (the genome position array) whose element number is the genomic position, and whose value is a unique numerical descriptor of the corresponding 13-nt sequence.
