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Numeric outcomes were analysed using Poisson generalized linear models and binary outcomes were analysed using Logistic generalized linear models.
The report contains global overall graphic and detailed numeric outcomes of the peers, co-workers and patients' evaluations as well as the self-evaluation.
A CI, while it has other interpretations, can be thought of as a range of numeric outcomes that we are reasonably confident includes the actual result.
The indexes were analyzed as numeric outcomes using a random model approach, with clinic and subject as random factors, and arm and strata as fixed factors.
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Similar models were made for the other numeric outcome measures.
Using ideas from qualitative research, it allows a rigorous approach to types of research question that cannot typically be addressed through clinical trials and numeric outcome studies.
If therapeutic change reported by a practitioner is confirmed by the patient's illness journal, GP, blood results, numeric outcome measures, spouse and by independent interview, then it can be said to have occurred beyond reasonable doubt.
Though this paper is focusing on qualitative methods there is no a priori reason why these cannot be combined with quantitative approaches using a wide spectrum of generic and condition-specific numeric outcome measures such as EQ-5D and MYMOP.
The heterogeneity of study designs and the limited numeric outcome data prevented the statistical pooling of findings, so the findings are presented in narrative form, ie, in a table.
In keeping with the case series methodology, this is done by triangulation of data from a range of different sources as listed in Table 3. Patient consultation and interview narratives were compared to their artwork, significant others reports, numeric outcome data and physician scoring to create an informal composite measure termed "global outcome assessment" or GOA.
Forty studies (one case series, three phase I, five pilot, 22 nonrandomized, and two randomized phase II, one randomized phase III study, data of three expanded access programs, three retrospective studies) with 841 evaluable patients were included in the numeric outcome analysis.
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