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Furthermore, due to limited sample amounts and large numbers of fractions to be tested, high-throughput low-volume bioassays are required [5].
Since the isolation and identification of individual toxicants out of thousands of components in typical environmental mixtures often demand for large numbers of fractions, high-throughput tools are preferred.
Results were basically similar for different intervals between fractions (10-900 s) and different numbers of fractions (2-25).
Reduced numbers of fractions will reduce radiotherapy costs in terms of work-hours and fewer fractions also results in fewer visits for a patient to the radiotherapy clinic, which is more convenient and less costly [17].
By delivering radiation doses higher than 10 Gy in a single fraction or 20 60 Gy in limited numbers of fractions severe vascular damage leading to the deterioration of the intratumor microenvironment and indirect death of tumor cells is observed.
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The average number of fractions used per patient was 1.9.
A lower number of fractions results in a lower latency.
Figure 10 illustrates the effect of limiting the number of fractions.
Chemical analysis showed that a number of fractions were found to exert a significant growth inhibitory effect.
The number of fractions was decided from received renal dose (limit 27 Gy) or persisting haematological toxicity or disease progression.
Total dose, dose per fraction, number of fractions and treatment time are important determinants of the biological effect of a radiation regimen.
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