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Next to objective quantification of inflammation, information about synovial metabolic activity, and an increased discernability of individual disease severity, this is a major advantage of this new and promising imaging technique, enabling a considerable contribution to the claim of reducing animal numbers in experiments.
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Furthermore, while the qualitative trends of the PL lifetimes are reproduced by the toy model, there are small deviations in the absolute numbers in experiment and in the toy model.
The numerically highest maximal numbers were found in experiment I, and the numerically lowest maximal numbers in experiment II.
For the low number spike-in experiments this tool was used to exclude cytokeratin-positive cells that lacked mCTC morphology.
This was achieved by combining a two-alterative forced choice psychophysics procedure with quantum light source; a tool that allowed us to eliminate the irreducible variability of photon numbers in previous experiments.
We used several frame selection numbers in the experiments.
Fig. 2 a Time series of the convective grid numbers in each experiment.
The numbers in our experiment are given in Table 1.
All of the drugs used, their doses, and final animal numbers in each experiment are listed in Table 1.
In the transfection study, Student's two-sided t-test was used to compare cell numbers in each experiment at 1, 2, 3 and 4 days after transfection.
Only by adjusting this was it possible to reproduce correctly the downstream evolution of particle number found in experiment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com