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Plasmid instability and copy number variance provide challenges for replicative plasmids, while use of homologous recombination for insertion of DNA into the chromosome is slow and laborious.
In addition to the previously mentioned samples filtered due to low quality, two Zulu samples were identified as having high copy number variance and removed.
CNPs are regions of copy number variance present in greater than 1% of the 270 HapMap samples, resulting in a library of 1,320 CNPs.
In effect the idea of bursting, which amplifies protein relative to mRNA number variance, applies here too, amplifying the variance of transcript number above the expectations from the Poisson distribution.
Both weediness and noxiousness are predicted by genus standard deviation for highest chromosome number – variance in chromosome number at the genus level probably reflects the prevalence of polyploid taxa.
Additionally, copy number variance in the HLA region has previously been reported in the literature[34].The duplication of this finding in a small cohort of patients indicates the importance of the MHC region on chromosome 6 in the genetic susceptibility to T1D and affirms that analysis of small sample sizes can yield biologically relevant results.
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The two exons of the fern ndhB gene have a unique pattern of intragenic copy number variances.
Second-order corrections are limited to three rate-limiting steps to avoid solving a huge number of variance and covariance equations.
The last illustration in this section (Fig. 9) shows the interdependence of the Rayleigh number and variance of temperature with time.
In this work we extend compound class modeling by following not only the concentration of each class but also the average carbon number and variance of the carbon number distribution for each compound class.
(a) Node consensus estimates x ̄ n ( k, J ) versus tracking time step; (b) node estimates x ̄ n ( k, j ) versus consensus iteration number; (c) variance of node estimates var k, j) versus consensus iteration number.
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