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Exact(6)
In addition to this, the number of stratification variables is also important with one single, LiDAR-derived variable (OV) leading to better estimates than two separate variables (OV + CC) for three of the four datasets and nearly equivalent estimates for the fourth.
These data provide adequate statistical power for the study across a number of stratification variables, and improves its generalizability.
By rationing the number of proposed strata we can impose a more considered choice on both the number of stratification variables and the number of levels of each (Choi et al, 1995).
The use of common statistical tests is in part due to the wide recognition of these tests, but also because it is extremely complex (if not impossible) to perform the correct permutation test when sample sizes, and the number of stratification factors, increase (Knijnenburg et al, 2009).
INCANT succeeded in randomizing study participants on a number of stratification variables, but one set of variables could not be included in the randomization process: the local treatment culture in a city/country, and the local referral and other treatment-related policies.
For the purposes of defining the number of stratification variables it is probably better to ignore centre, unless there are only a few and the variation in outcome between them is comparable to that found with a prognostic factor such as tumour stage.
Similar(54)
The number of stratifications was set to equal the number of iterations performed.
A number of stratifications were performed to assess the robustness of results.
A number of stratifications and sensitivity analyses will be performed to confirm the results.
Using statistical significance alone, almost all the variables in Table 1 would be identified as interacting variables, causing an impossible number and hardly meaningful number of stratifications.
We used Bonferroni correction to account for the number of stratifications – with 12 strata for survival and 13 for volume data (1 extra stratifications for the method of volume measurement) giving critical values for significance of P=0.0043 and P=0.0039, respectively.
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