Experiments with the NAS Parallel Benchmarks showed a reduction of up to 13.9% of the execution time, 30.5% of the cache misses and 39.4% of the number of invalidation messages.
The low number of invalidation decisions made for the true model relate to the high specificity of our approach.
In Table 4 we report the number of invalidation decisions made for the two models and Figure 11 show the kinetic model and SPCA predictions on this dataset.
Overall, 27% of invalidations are pairs of terms with identical names.
The efficiency of invalidations has been monitored by western blots, and programmed cell death was estimated by DEVDase activity.
While a number of NR has been studied, it is unknown whether invalidation of the pregnane xenobiotic receptor (PXR, NR1I2) corresponds to neurological modifications in the adult brain.
A word of caution is however needed concerning CD28 invalidation as it may alter a number of other immune parameters than the production/differentiation of CD4+CD25+FoxP3+ regulatory T cells and 3) the involvement of NKT cells demonstrated by the absence of diabetes protection in CD1d−/−NOD mice that are deprived of NKT cells [45].
Nevertheless, the absence of S phase overt perturbation in crypts from PrPc null mice, as shown by BrdU incorporation experiments, along with the important increase of the number of mitotic cells in the crypt compartment suggest that PrPc invalidation would affect the mitosis process.
Applied in this way, model invalidation can be used to reduce the number of possible models [ 7], hence narrowing down the number of possible network connectivities.
Therefore, the problem of model invalidation turns to a problem of model selection between a number of models with similar complexities.
We use a per-user proxy to buffer invalidation messages to allow the MH to disconnect arbitrarily and to reduce the number of uplink requests when the MH is reconnected.
