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Both types of trial record the occurrence of seizures over a set period from which a large number of endpoints may be derived for analysis.
The MJPs with indexes corresponding to the number of endpoints constraints are the natural basis functions for Least-square approximation of Bézier curves.
Two phase II gefitinib ('Iressa', ZD1839) monotherapy trials, IDEAL 1 and 2, investigated the effect of gefitinib on a number of endpoints, including disease-related symptoms and QoL, in patients with refractory advanced NSCLC.
Within any particular trial, the required sample size will depend crucially on the characteristics of the population sampled, the type (and perhaps number) of endpoints, losses to follow-up and other deviations from protocol, as well as important statistical considerations, especially the type of design, including Type I and II error rates, and methods of analysis.
The sample size for simultaneous testing is not only determined by Type I and II error rates, but also by several other factors including the effect sizes of each endpoint, the number of endpoints and the correlation among test statistics in each endpoint.
Each component has a number of endpoints, which can be thought of as typed communication ports.
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This protocol outperforms an alternative quantification using the difference in the number of endpoint PCR replicates with positive detections, even in samples with low DNA presence37.
Duke University IT staff utilize a number of endpoint management services to support efficient maintenance of computing devices.
a Pops with CI: Total number of populations in each treatment (harsh versus benign) showing evidence of CI (as determined in Table 2); Pops with no CI: Total number of populations not showing evidence of CI. b Number of endpoint populations with or without evidence of CI pooled across both ancestors.
We evaluated the frequency of CI by determining the number of endpoint populations where CI was present or absent and comparing these frequencies between treatments by a Fisher Exact Test (see Discussion and Table 3 for criteria used to identify CI; Tables 2 and 5).
Results for 3 of these 36 comparisons (one permuted dose group compared against placebo for 3 of the 9 endpoints), and the number of endpoint comparisons out of 9 with a positive trend for that dose group, are shown for the 10 illustrative permutation samples in Table 3.> -wrap-foot> * Positive trend defined as one-sided P < 0.10 † One-sided One-sided Pours relaxin and P > 0.5 favours placebo.
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number of predictors
proportion of endpoints
number of endings
incidence of endpoints
number of considerations
number of deliverables
number of conditions
multitude of endpoints
number of criteria
number of components
number of systems
number of incidents
number of elephants
number of elections
number of counterproofs
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