The mortality rate increased with increasing number of organ dysfunctions: BIDMC: 0 organ dysfunctions, 0.6% mortality; 1 dysfunction, 3.3%; 2 dysfunctions, 7.8%; 3 dysfunctions, 15.9%; and ≥4 dysfunctions, 34.3%; and AUH: 2.2%, 6.7%, 17%, 41%, and 57% mortality.
Plasma sVEGFR1 level and uPA activity had good correlation with renal dysfunction, metabolic acidosis, and hematologic dysfunction; their levels significantly increased when the number of organ dysfunctions increased.
There were no differences in the occurrence of other organ dysfunctions between the two groups or in the overall mean number of organ dysfunctions.
In the intensive care unit (ICU), almost all adult and pediatric patients present some organ dysfunction [ 1– 5] and mortality rates increase with the number of organ dysfunctions [ 5– 8].
Non-survivors have significantly higher initial, mean, and highest SOFA scores and more number of organ dysfunctions after 48hours.
Exposure to ethanol during development induces severe brain damage resulting in a number of CNS dysfunctions including microencephaly and mental retardation in humans and in laboratory animals.
If emotions are repressed for a long time, this can lead to a number of mind/body dysfunctions, such as suppressed emotions, especially anger, sleeping disturbances, dizziness, fatigue, a feeling of obstruction in swallowing, indigestion and bowel dysfunctions [27].
Patient records from the last 3 years from 2011 through 2013 were studied (n = 104) to examine outcomes of hospitalized patient in terms of number of organ dysfunctions, ICU length of stay, hospital length of stay and mortality in patients infected with MDR AB infection compared with the patients with MDR non-AB infection.
