Sentence examples for number abnormality from inspiring English sources

Patients were determined to have a normal RB1 pathway if CDKN2A, CDK4 and RB1 had normal copy number, and to have an abnormal RB1 pathway if any one of these had any copy number abnormality.

The rate of chromosome number abnormality in porcine sperm was found to be 6.25% (70/1120).

Eight transformed clones (SVFN1-8) were isolated from the soft-agar plates and grown into individual cell lines and their genomic DNA extracted for genome-wide SNP array profiling (Fig. 5A) to obtain genomic instability in the form of loss of heterozygosity (LOH) and copy number abnormality (CNA).

Of those with an aberrant IC1 methylation profile, three (0.3%) individuals had a copy number abnormality (all duplications), while of those who had an aberrant IC2 methylation profile, one (0.1%) individual had a copy number abnormality (deletion).

DNA copy number abnormality was assessed by a molecular inversion probe (MIP) platform with focal amplification and high resolution (~10 K bp) as previously described [ 24– 26].

Recent studies revealed a high frequency in copy number abnormality of miRNA processing genes, such as Dicer1 and Argonature2, in breast and ovarian cancers [ 28, 29].

Synthesis of comparative genomic hybridization (CGH) and spectral karyotyping (SKY) results revealed that chromosomal rearrangement is involved in DNA sequence copy number abnormalities throughout the genome, but monosomy 3 was not found.

Considering the whole patient population, there was no statistically significant increase in copy number abnormalities from diagnosis to the relapse.

This study compared t-AML to p-AML using high resolution array CGH in order to find copy number abnormalities (CNA) at a higher resolution than conventional cytogenetics.

Lrp4 mutants display a range of tooth number abnormalities that are identical to those seen in Wise mutants and include fused molars and supernumerary incisors and molars.

Affymetrix 500K SNP array analysis revealed all paediatric glioma cell lines to display complex genomes with numerous gross chromosomal copy number abnormalities and rearrangements.