Sentence examples for null system from inspiring English sources

"The wild is a null system, a system without interference," said Peter J. Hudson, a biologist at Penn State and a founder of the infectious disease center there.

The Huh7 human hepatoma cell line exhibits low level expression of PXR under normal conditions, and usually require addition of a PXR expression plasmid to elicit activation of reporter gene assays [30], primarily due to altered chromatin status [31]; they thus represent a near-PXR null system.

FBXW7 functional studies have generally used null systems.

The transfection of TMEM16A coding sequence in null systems such as HEK-293 cells generates Ca2 +-dependent Cl− currents [1 7].

Apart from being useful for studying the mechanism of spindle formation, DNA bead-spindles may provide a clean kinetochore-null system for observation and dissection of the poleward forces exerted on the chromosomes.

At constant flow, the pressure gradient generated in the tumour by the infusion of fluid (Evans blue-albumin in saline) was measured as a function of the radial position with micropipettes connected to a servo-null system.

We are in the process of using the same cell lines to test for changes in sensitivity to DNA-damaging agents with respect to signaling to apoptosis, and it is possible that cells carrying MBD4tru mutations will also be more tolerant of the types of damage tested in Mbd4-null systems.

This algorithm requires a null linear system solving, and a constraint is required to prevent the trivial solution.

As the NMD pathway affects both mRNA isoform distributions as well as transcript levels, unraveling the underlying molecular mechanism(s) for the NMD requirement in proliferation will require full whole-transcriptome mapping studies of NMD deficient mammalian cells as well as the development of a conditional NMD null cell system amenable to rescue experiments.

Thus, we wanted to first assay for biochemical differences in MMP1 expression and activity in the dfmr1 null nervous system.

Kin- cells, a clonal, cAMP-resistant S49 variant that lacks PKA activity and expression of the catalytic subunit of PKA, provide a null cell system for identifying cAMP/PKA-dependent responses.