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XRCC1 null cells were slightly more sensitive to SIN-1 than wild-type cells.
Further, we show that disruption of Rho1 suppresses apical constriction and invagination in APC null cells.
In contrast, 4-AN had no effect on repair in Pol β null cells.
Engineered FBXW7 null cells display cell cycle and chromosome stability defects.
Cells expressing LigI were more sensitive to L82-G17 than isogenic LIG1 null cells.
MMS exposure strongly increases mutant frequency in β-pol null cells, but not in wild-type cells.
Similar(17)
Highly selective killing of Pten-null cells can be achieved by deguelin, a natural insecticide.
Possibly in conjunction with this defect, dDia1-null cells also formed substantially smaller fruiting bodies.
DYRK2-null cells exhibit lowered proteasome activity and slowed proliferation, phenocopying Rpt3-T25A knock-in.
Open image in new window Figure 6 c-Jun regulates TGFβ expression in IKKβ-null cells.
There are at least two sources for the ROS in IKKβ-null cells.
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