Sentence examples for null brain from inspiring English sources

Histopathological analysis of Txnrd1 null brain revealed striking cerebellar hypoplasia, in particular of lobules I VI.

Drops in mitotic cells and cells in S-phase along with reduced expression of the N-myc target gene cyclin D2 were considered being responsible for cerebellar hypoplasia in N-myc null brain.

Later, another study using PDGF-B driven Ink4A-ARF null brain stem glioma model demonstrated non-effectiveness of perifosine in a pre-clinical trial as a single agent [33].

In contrast, 60% of Braf mRNA in E18 null brain, and 41% of the mRNA in P5 EmxKO cortex contains the exon.

Licatalosi et al. also report microarray identification of PTBP2 target exons in germline null brain that largely overlap with exons we identify in the pan-CNS knockout brain by microarray and by RNAseq.

In the PTBP2 null brain these exons exhibit adult levels of splicing at E18. (C ) The premature switch in CAMK2B protein isoforms is observed by immunoblot in both Ptbp2 null (KO) and NesKO mice (E18.5-P0 E18.5-P0

We found clear expression of MMP1 in the nervous system, but no detectable difference between control, dfmr1 50M heterozygous and dfmr1 50M null brains (supplementary material Fig. S1).

Cell proliferation was severely impaired in the DG of Dicer null brains, confirming that miRNAs are necessary for the hippocampal development.

Consistent with earlier reports (Gatto and Broadie, 2009b), dfmr1 50M null brains showed increased numbers of sLNv clock neuron PDF-reactive synaptic boutons in dorsal protocerebral projections (45±4.4 control vs 67±6.3 dfmr1 null; n≥12; P<0.01; Fig. 2A,B).

Anti-PDF staining of these small ventrolateral (sLNv) clock neurons in dfmr1 null brains revealed an increased number of synaptic boutons, with overextension of their spatial distribution extending from the dorsal horn bifurcation point (Fig. 2).

(A ) Representative drawings of Golgi stained CA1 hippocampal neurons from control and Aph1bc −/− null brains at P30. so, stratum oriens; sp, stratum pyramidale; sr, stratum radiatum; slm, stratum lacunosum moleculare.