Sentence examples for nucleus failed from inspiring English sources

They showed 2 defects: incoming capsids failed to migrate to the nuclear margin following membrane fusion, and genomes that did reach the nucleus failed to initiate normal gene expression.

The relative increase in circular over linear ORF75c− genomes on Gardella gels of infected cells (Fig. 5B) argued that some ORF75c− genomes reaching the nucleus failed to initiate lytic replication.

In an apparent contradiction, expression of ICP0 from a tetracycline-inducible plasmid system, which restricts ICP0 expression to the nucleus, failed to block ISG induction following IFN or dsRNA treatment [37].

97 Furthermore, a SIRT1 NLS mutant unable to enter the nucleus failed to suppress colony formation, whereas SIRT1-overexpressing cells showed a strong inhibitory effect.

During semigamy, the sperm and egg cells undergo cellular fusion, but the sperm and egg nucleus fail to fuse in the embryo sac, giving rise to diploid, haploid, or chimeric embryos composed of sectors of paternal and maternal origin.

Activation of paGFP was achieved by irradiation from a single-photon diode laser at 408 nm, but activated nuclei failed to divide.

In addition, isolated nuclei failed to activate RhoA following IR when Net1 expression was silenced (Figure 5E F).

In mosaic egg chambers possessing large PFC clones of hpo or sav mutations, oocyte nuclei failed to migrate and remained at the posterior after stage 7 95%% in hpo, n = 63; 93% in sav, n = 76) (Fig. 1G,J).

Importantly, stimulation of other thalamic nuclei failed to evoke similarly widespread activity in the striatum and cortex.

In the absence of MeCP2, the neuronal nuclei fail to increase in size at normal rates during cell differentiation.

Therefore, DNA methylation alone on the Xi in donor nuclei fails to explain the difference between Xi(diff) and Xi(Epi) reversibility following nuclear transfer.