Sentence examples for nucleus bound from inspiring English sources

Like most other nuclear receptors that form heterodimers with RXRs, LXRs reside within the nucleus, bound to LXR response elements (LXREs) and complexed with corepressors.

Glucokinase is located in the nucleus, bound to GKRP as an inactive complex under basal glucose conditions.

Unlike CAR, which appears to be primarily found in the cytosol and constitutively expressed in humans, PXR is especially found in the nucleus, bound to several co-repressors.

Our genetic analyses combined with the structural analyses reported in Kadlec et al. (26) support a model in which Upf3p exports from the nucleus bound to Upf2p.

CREB1, which belongs to the CREB/ATF family of transcription factors, is predominantly located in the nucleus bound to CRE and is activated by phosphorylation at Ser in the kinase-inducible domain.

DEX (Marchetti et al. 2003) and DES (Ahmed 2000), synthetic hormones that bind to the glucocorticoid and estrogen receptors, respectively, translocate to the nucleus bound to the receptors and regulate gene expression and protein synthesis.

Intracellular PKAcα levels and phosphorylation of HSF1 at S320 were both required for HSF1 to be localized to the nucleus, bind to response elements in the promoter of an HSF1 target gene (hsp70.1) and activate hsp70.1 after stress.

The degradation of I κB releases the transcription factors NF- κB, which translocates to the nucleus, binds the κB site and activates gene transcription.

For a gene trap to be detected, this fusion protein has to enter the nucleus, bind the 14XUAS and activate eGFP expression.

The phosphorylated STAT proteins move into the nucleus, bind specific DNA response elements, and directly transcribe IFN-stimulated genes to induce an antiviral immune response.

They then translocate to the nucleus, bind DNA response elements and drive the transcription of target genes, affecting growth, differentiation, homeostasis and the immune response [ 1].