Sentence examples for nucleotide point from inspiring English sources

We generated the complete set of single nucleotide point mutants and tested their transcription activity.

These aberrations include single nucleotide point mutations, changes in chromosome copy number [9], [10], and specific genomic amplifications or deletions that are implicated in the pathogenesis of lung tumor development and progression through the activation of oncogenes and inactivation of tumor suppressor genes [11], [12], [13], [14], [15], [16].

Genetic examinations of the SCN5A gene at 6 positive patients showed 6 known polymorphisms, 8 new single nucleotide point (SNP) variants located at exons, and 12 new single nucleotide point variants located at introns.

Both methods typically use a single nucleotide point, the midpoint or mode of the peak, to represent the entire peak region.

In approximate tandem repeat, a small number (no more than 30%) of characters in pattern copies are distorted by indels and nucleotide point mutations.

This was shown to be the result of a single nucleotide point mutation within the chs2 chitin synthase involved in cell wall biosynthesis (Brunke et al. 2014).

When comparing genomic DNA, the extreme nucleotide points offer a better view of the differences between sequences than ones near the origin.

The parameters of T are therefore estimated by the 4 × 4 matrix of observed nucleotide point-mutations n ij.

The resulting approximately 12 copies of the gene when compared with just two copies in 90-125 are distributed over five chromosomes and are all identical at the nucleotide level, pointing to a recent expansion.

In all but one case, the null model was a single-nucleotide "point substitution" model that was reversible and strand-symmetric (but otherwise fully general).

Secondary mutations in BCR-ABL are mainly single-nucleotide point mutations of the kinase domain, deletion or insertion mutations are rare.