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Methylation of CG and CWG sites is maintained by different mechanisms: CG sites are maintained by a plant homolog of mammalian Dnmt1 acting on hemi-methylated DNA after replication [ 57] whereas methylation of CNG sites (N is any nucleotide) is maintained by other mechanisms.
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The endogenous supply of nucleotides is maintained through de novo synthesis and salvage pathway.
The cycling order of the nucleotides is maintained throughout the sequencing process (T, A, C, G representing one flow cycle).
That is, activated AMPKα1 suppressed ATP-consuming metabolic processes to balance the rate of ATP production and consumption and thereby the ratio among adenine nucleotides was maintained at the constant level [32].
With this strategy information about nucleotide coverage is maintained which is important for reliable SNP discovery.
Although this domain lacks the phosphotransfer activity, nucleotide binding is maintained and required for the assembly of a functional RNase dimer (Huang et al. 2014).
Therefore, the clustering pattern among the six nucleotide sequence classes is maintained in Eukarya but changed in Archaea and Bacteria due to sequence bias in datasets.
In summary, although a fraction of the Nc nucleotides within SSs is maintained by selection, the abundance of deleterious nucleotides in this class suggests a substantial genome-wide drift load.
Specific environmental conditions (in this case: no pairing with Cyt18 while base stacking is maintained) can change the conformational behavior of a specific nucleotide position in unexpected ways.
During the shuffling procedure, the single-nucleotide frequency of each sequence is maintained, but the nucleotide order is randomly shuffled.
These results further support the hypothesis that increased nucleotide diversity in SDHA is maintained by balancing selection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com