Sentence examples similar to nucleotide interruption from inspiring English sources

Because miRNA targeting has a stringent requirement for consecutive base pairing at the 5'-end of the miRNA[30], even single nucleotide interruptions to this base pairing can dramatically affect the efficacy of miRNA binding, and consequently be deleterious[31], [32].

The G702D mutation affects a glycine residue separated by six Gly-X-Y repeats from a 24-nucleotide interruption in the Gly-X-Y repeats of COL4A2 (interruption XIII within COL4A2 (24)).

BPCR has the potential to be developed into a method for the detection of nucleotide backbone interruptions or other factors that impede 3' extension by polymerase.

In addition, while the CbfA binding site mapped in the acaA upstream region contains an oligo dT) tract of 52 nucleotides length, its interruption by blocks of 10 adenine bases abolished the binding of CbfA to the altered DNA fragment in gel shift assays [9].

I am constantly interrupted, interruptions engendered by other interruptions.

Both segments (A and B in Figure 2a) contain approximately 60 repeat interruptions (mainly single nucleotide substitutions).

Two neighboring SSRs with the maximum interruption no more than 100 nucleotides were considered as a compound SSR.

The search was restricted to motifs having at least 14 bp length (i. e., di-nucleotide > 7; tri-nucleotide > 5; tetra-nucleotide > 4; penta-nucleotide > 3 and hexa-nucleotide > 3) and the minimum difference between two SSRs in a sequence (interruption) was 100 bases.

For the modified strand, the sequential connectivity was observed from G to C. Because the S-cdG nucleotide lacked a proton at the C8 carbon, the sequential connectivity exhibited an interruption at X.

High acidic amino acid composition in the TPR2 interruption region has been maintained by the presence of strong selection which in turn has biased the nucleotide composition in the corresponding NASP gene.

The maximum interruption between 2 SSRs to consider a SSR as a compound one was set at 100 nucleotides.