Sentence examples for nucleotide integrity from inspiring English sources

On the other hand, the strict nucleotide integrity of the upstream PPTs, their high copy number and preferential clustering next to the 3'LTR point towards selection.

The pET4641 insert was sequenced to confirm the nucleotide sequence integrity of the cloned gene.

An emerging striking observation is that by transcriptional activation and other means, p53 is able to contribute to the regulation of several pathways as oxidative phosphorylation, glutaminolysis, insulin sensitivity, nucleotide biosynthesis, mitochondrial integrity, fatty acid oxidation, antioxidant response, autophagy and mTOR signaling.

Consequently, manual reconstruction by detailed inspection of each and every reaction, biomass equation based on metabolic building blocks (such as amino acids and nucleotides), consistency and integrity of the network is a pre-requisite for creating a high quality and useful metabolic model [ 31].

Full-length sequencing of the final construct was performed to verify the nucleotide changes and the integrity of the ADRB2.

In order to maintain codon integrity the nucleotide sequences were then aligned to the amino acid alignment.

In order to evaluate the HPV16 integrity and nucleotide sequence alterations within the intact E2 gene, we performed bidirectional sequencing of the PCR products obtained using the specific primers [ 21].

Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers.

As a control for DNA integrity, a 124 nucleotide (nt) section of the human beta-globin gene was amplified.

The amplified DNA fragments were first cloned into pCR2.1 vector and sequenced to ascertain the integrity of the nucleotide sequences.

However, unlike Golgi localisation, localisation to the endolysosomal system also requires the functional integrity of the nucleotide binding site, and thus probably reflects transient activation.