Sentence examples for nucleotide based on from inspiring English sources

This is consistent with their proposed roles in the coordination of metal ions and the formation of a bond between primer and the incorporating nucleotide based on crystal structures [7]; [7]; [7]].

P-values were computedfor each nucleotide based on Wilcoxon rank sum tests, with the alternative hypothesis that the unpaired probability in predicted binding sites are higher than controls.

Pol δ was shown to have high selectivity for the correct nucleotide based on kinetic studies of the insertion of individual dNTPs opposite a known nucleotide in a DNA template.

Individual SNPs were scored by PCR using forward and reverse primers that differ only at the 3′ terminal nucleotide, based on the DNA sequence of the gene in ER18 or 16D.

Similarly, the sequence difference between the closely related L. inadai and L. broomii is 3 nucleotides based on the nearly entire gene and a single nucleotide based on the 443-nucleotide rrs region.

Tajima's D is the difference between two estimates of the expected amount of genetic variation per nucleotide, based on the number of segregating sites S, and on average number of pairwise differences ∏, respectively [ 98].

SND density was set to be one per seven nucleotides based on the 85% sequence identity between the two species.

When possible, Mega5 software was used to manually correct ambiguous nucleotides based on the chromatograms [ 51].

Unlike previous studies we do not adjust binding strength for nucleotides based on their position on the probe [ 14].

We allowed the inter-domain separation to range from 1 to 6 nucleotides (based on an average inter-domain distance of 4.5 nm (Petoukhov et al, 2006).

Additionally, the 3′-end of the guide RNA was extended by five nucleotides based on the native sequence of the S. pyogenes tracrRNA (Deltcheva et al., 2011).