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They summarize a mixture of factors, incorporating the nucleotide availability among others.
The replication fork speed was found to be gradually reduced proportionately to moderate reductions in nucleotide availability.
Our findings suggest specific and synergistic mechanisms for the control of nucleotide availability throughout the stratified layers of the bladder.
Despite the potential involvement of epigenetic factors, transcriptional regulation and nucleotide availability, the causes of differences in replication times during DNA synthesis have not been established satisfactorily, yet.
A broad expression profile at the level of mRNA for all of these enzymes was observed suggesting the presence of complex cellular and tissue regulation of nucleotide availability as well as a substrate scavenging capability.
CtpS tetramerization is necessary for its catalytic activity and is controlled by nucleotide availability; ATP, UTP, or CTP can favor tetramer formation.
Similar(52)
The glycosylation pattern of proteins depends on multiple factors, including enzyme activity, nucleotide sugar availability, kinetics of glycoconjugate transport, and cell type/stage.
This process is subject to various fluctuations, like nucleotide-specific polymerization kinetics, substrate availability (diffusion of the nucleotides), mismatch control (wrong nucleotides arriving at the polymerization sites but not being processed) and malfunctions that potentially cause delays.
This suggests that the ugd2,3 mutant is compromised in some of the nucleotide sugars, limiting the availability of them for glycosyltransferases [ 5, 6].
The second direction (Section 2.3) requires structural information about the binding interfaces, reasonable prediction of the tertiary structures of nucleotide sequences, and the availability of immense computational resources.
It seems intuitive to assume that there are fluctuations, e.g. in the availability of nucleotides in the nucleus.
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