Sentence examples for nucleotide at a time from inspiring English sources

The hooking together of free nucleotides in the newly synthesized strand takes place one nucleotide at a time in the 5′ → 3′ direction.

When a cell divides, the strands peel apart, and DNA polymerase builds matching strands one nucleotide at a time.

PWM1, PWM2 and PWM3 matrices were used individually to scan entire genome sequences, one nucleotide at a time, by a sliding window method as described previously [31].

For instance, groups of two consecutive nucleotides were extracted by walking one nucleotide at a time from one end of an AON target site to the other end.

In our analysis, to approximate transcription elongation, a "window of analysis" that included the entire targeted exon was shifted one nucleotide at a time along the pre-mRNA.

Based on the multiple alignment of all its occurrences, the program extends this consensus one nucleotide at a time, in both directions, according to a specific scoring function.

While many GWAS results have been reported analyzing single nucleotide polymorphisms (SNPs) one-at-a-time, only recently have studies begun to extend analysis methods to consider interaction effects between pairs of loci (Cordell, 2009; Curtis, 2007; Emily et al., 2009; Gayan et al., 2008; Herold et al., 2009).

In this translation, the sequence of nucleotides in the messenger RNA chain is decoded three nucleotides at a time, and each nucleotide triplet (called a codon) specifies a particular amino acid.

Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time.

The mRNA is loaded onto the ribosome and is read three nucleotides at a time by matching each codon to its base pairing anticodon located on a transfer RNA molecule, which carries the amino acid corresponding to the codon it recognizes.

The ANACONDA 1.0 algorithm developed previously [20], [29] simulates the ribosome during decoding by reading Open Reading Frames (ORFs) sequences, starting at the AUG initiation codon and moving the reading window three nucleotides at a time (Figure 1A).