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As recently reported, prior mitotic remodeling of the somatic nuclei, involving topoisomerase II (TOP2 -dependent shorTOP2 -dependentatin loop domainshorteningncreased recruitment of replichromatinitiation factors onto chromatin, is essentialoopr reprogramming of domainsntiandd nuclei [ 26].
A term of sign (−1) s +1 in the polynomial necessarily corresponds to a collection of nuclei involving at least one positive feedback loop, see Section ' The polynomial and circuits'.
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The disorder is characterized by the progressive degeneration of the basal ganglia of the brain (large group of nuclei involved in the control of movement), the development of a brownish ring at the margin of the cornea, and the gradual replacement of liver cells with fibrous tissue.
The number densities of the nuclei involved were estimated from the chronoamperometric measurements.
Further, hypocretinergic input to nuclei involved in autonomic control may be particularly interesting in this regard [107].
This approach was far better at simulating the motion of electrons and atomic nuclei involved in chemical reactions.
Moreover, the descending modulatory influences of cortical areas on brainstem nuclei involved in pain control and their potential role in precipitating migraine attacks have been recently described [53, 54].
With this in mind, the challenge is to dissect the contributions from a change in homeostatic pressure and a change in function of the hypothalamic and brainstem nuclei involved in the regulation of sleep and pathology of headache.
However, dysfunction of the regulation of brainstem nuclei involved in anti-nociception and extra- and intracerebral vascular control provides an encompassing explanation for many of the facets in migraine [18, 52].
We investigated the effects of the nigrostriatal lesion on behavioral responses to pain tests designed to explore different aspects of nociception, such as the formalin test and the tail flick test; we also explored modifications in the expression of Fos protein, a marker of neuronal activation, in supraspinal nuclei involved in the integration of pain perception and stress-related behavior.
Exposure to these "legal highs" results in symptoms similar to those of well-known substances such as phencyclidine, amphetamines or cocaine, probably because they share mechanisms of action related to dopamine reuptake in brain nuclei involved in the regulation of reward behavior.
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