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Nuclear volume is constant thus Cln3 abundance directly reflects Cln3 nuclear concentration.
In addition, nuclear area (NA), nuclear volume (NV) and the ratio of nuclear volume/cellular volume (N/C) were measured in the liver.
The nucleus was also elongated as nuclear height increased, but the nuclear volume remained intact.
Telomere signal intensity, number of telomere aggregates, nuclear volume, and the overall nuclear telomere distribution (a/c ratio) were analyzed.
Roca-Cusachs, P. et al. Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation.
Nuclear volume was osmotically sensitive but this relationship was not linear, showing a decline in the osmotic sensitivity in the hypo-osmotic range.
Moreover, we found a significant increase in nuclear volume in asymptomatic AD compared to controls (P<0.001), MCI (P<0.01) and AD (P<0.001) brains.
All territory volume measurements were normalized to nuclear volume.
3-D confocal imaging and measurement of the nuclear volume confirmed that LmnaDhe/+ cells had a larger average nuclear volume than Lmna+/+counterparts (p≤0.001, Student's t-test).
In fact, the nuclear volume does not seem to change in the myosin-inhibited embryos.
However, measurements of total nuclear volume (defined by H2B-RFP) suggest this is not the case.
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