Sentence examples for nuclear trail from inspiring English sources

The way it's going now, should anyone be surprised that Iran is speeding along the wayward nuclear trail blazed by North Korea?

Another study investigating human nuclear TRAIL receptors finally uncovered specific functions of nTRAIL-R2 connecting this receptor to the process of miRNA maturation.

The nuclear TRAIL-R2-driven decrease in mature let-7 enhances the malignancy of cancer cells.

Nuclear TRAIL-R2 interacts with the Microprocessor complex, inhibits let-7 maturation and enhances tumor cell proliferation.

The authors report that nuclear TRAIL-R2 (nTRAIL-R2) is engaged in microRNA (miRNA) maturation, thus performing functions entirely different from its classical role as a plasma membrane-located signal transducer.

Here we review the diverse functions of TRAIL-R2 depending on its intracellular localization and we particularly discuss the nuclear TRAIL-R2 (nTRAIL-R2) function in the context of known nuclear activities of other normally plasma membrane-localized receptors.

Coal and nuclear both trailed in the rankings.

Now, a first study has demonstrated a functional impact of the nuclear localization of TRAIL death receptors in cancer cells.

This is consistent with studies of apoptosis in melanoma cells that have reported nuclear localisation of TRAIL R2 and may be one possible mechanism of escape from apoptosis [ 46].

The nuclear presence of TRAIL death receptors represents a new example of plasma membrane receptors that can localize to the nucleus, where they elicit functions distinct from their canonical signal transduction pathways that originate at the plasma membrane.

Another study demonstrated that inhibition of the nuclear import of TRAIL-R2 sensitized HeLa and HepG2 cells to TRAIL-induced apoptosis.