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These samples derive from mass lesions in mediastinum or lymph nodes and are composed of small- to medium-sized blast cells expressing nuclear terminal deoxynucleotidyl transferase.
Marlétaz and Le Parco do not give the nuclear 3' terminal region of the RPS8 type II gene which could reveal interesting features; for example, some of our unpublished studies have shown that intergenic regions are sometimes very short, evoking a very probable operon structure.
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It has been reported previously that the C2-L1Tc protein located in the Trypanosoma cruzi LINE (long interspersed nuclear element) L1Tc 3′ terminal end has NAC (nucleic acid chaperone) activity, an essential activity for retrotransposition of LINE-1.
Another characteristic event related to the nuclear changes during terminal differentiation is translocation of the N-terminal fragment of profilaggrin into the nucleus.
Intracellular localization of axotrophin is determined by an N-terminal nuclear targeting signal and a C-terminal nuclear export signal.
Each designed ZF-coding sequence was cloned between the N-terminal nuclear localization signal and the C-terminal NF-B p65 activation domain.
CRC: Colorectal cancer; NSAIDs: Nonsteroidal anti-inflammatory drugs; COX-2: Cyclooxygenase-2; ACF: Aberrant crypt foci; AMPK: AMP-activated protein kinase; PCNA: Proliferative cell nuclear antigen; TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling.
There is strong concordance between identified nuclear clusters and terminal mtDNA clades (Fig. 2).
The latest stage of Eve expression was chosen in order to determine as closely as possible, the terminal nuclear number in the DA1 muscle.
We assessed nuclear monophyly of terminal clades resolved in the mtDNA haplotype tree and for previously described taxa by filtering the nuclear Bayesian posterior distributions for trees that meet that constraint of monophyly for specified groups.
To verify the surprising novel interaction found between TAF8 and SPT7L in vivo, we expressed a truncated form of TAF8 that lacks its C terminal nuclear localization signal (NLS).
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