Localized plasma membrane and nuclear surface area (NSA) stretches were observed for both the cell compression and stretching simulation configurations.
Protein expression on the nuclear surface became less as detected by ki-67, a nuclear proliferation associated antigen expressed in all active stages of the cell.
This model is designed to incorporate uncertainties in the nuclear surface tension and in the proton chemical potential in a gas of dripped neutrons.
Resonant spectroscopy of short-lived nuclei produced in nucleus nucleus collisions can provide information on the nature of the nuclear surface and the formation of clusters.
Also, the researchers were surprised to see that some particles, after floating toward the nucleus, hopped aboard microtubule-based "tracks" on the nuclear surface and began to move in a straight line.
Mitogen-stimulated lymphocytes of 20 Down syndrome (DS) patients with regular trisomy 21 contain more condensed chromatin surface (11.28 ± 2.64%% of the total nuclear surface: mean ± SD) and more nucleolus organiser regions surface (13.21 ± 3.45 %) than that of 12 healthy controls: (8.84 ± 2.23 and 9.12 ± 2.33 %, reciprocally).
At the same time, the nuclear surface became the dominant site of microtubule nucleation (60%).
Large amounts of centrosome proteins relocalize to the nuclear surface at the onset of differentiation [6] [8].
Likewise, in a differentiating muscular cell, the nuclear surface may recruit centrosome proteins from the large cytoplasmic pool.
We reported previously that at early stages of differentiation, the centrosome proteins pericentrin, PCM-1 and cdk5rap2 repartition between the pericentriolar material and the outer nuclear surface [8].
To gain further insights, we tested whether the nucleation capacity of the nuclear surface correlated with the amount of accumulated centrosome protein (Fig. 3C).
