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Wiblin, A.E., Cui, W., Clark, A.J. & Bickmore, W.A. Distinctive nuclear organisation of centromeres and regions involved in pluripotency in human embryonic stem cells.
Here we will evaluate evidence implying that the folding of DNA is important for transcriptional control in mammals and we will discuss novel high-throughput techniques expected to further boost our knowledge on nuclear organisation.
The enormous antigen receptor loci in lymphocytes are a paradigm of dynamic nuclear organisation, which is integral to their need to move extensively in 3D space to achieve distal gene synapse for V(D J recombination and allelic exclusion.
Interest in chromosome architecture and dynamics has been revitalised by demonstrations that chromosome position and nuclear organisation contribute to gene regulation [23], [24], [25], [26].
Where all the studies agree is that some changes in nuclear organisation do occur, and this is reflected in the 4Cv results.
The assembly of specific regions of eukaryotic genomes into heterochromatin is important for processes such as gene silencing, nuclear organisation, development, dosage compensation and chromosome segregation.
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These analyses demonstrated an ordered compartmentalisation, indicating a complex sub-nuclear organisation that contributes to the complexity of transcriptional regulation in P. falciparum.
Although its title sounds like a post-apocalyptic video game, Prayer Cycle 2: Path to Zero is a "classically influenced" benefit LP for anti-nuclear organisation Global Zero.
Through the columns of the Guardian women's page, edited by the late Mary Stott, she founded the anti-nuclear organisation Voice of Women after the Cuban missile crisis of 1962, when the world seemed on the verge of nuclear war and she was the mother of two young children.
It is one of the few anti-nuclear organisations able to employ full-time professional staff.
Voice of Women grew in strength and influence, and joined other anti-nuclear organisations demonstrating against the testing and proliferation of nuclear weapons throughout the 1960s.
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