RCC1 levels were used as a nuclear fraction indicator.
ICV injection of ASO-20-37 ASO-20-37 ASO-20-37d decresulted the number of SMN-containing nuclear gemarkedindecreaseof SMN protein abundance (Cooverthet al, 1997) inumbertof neurons (Fig 4), which is expected to cause nuclearl dysfunction.
The tests were used to identify nuclear disruption, an indicator of apoptosis.
Evidence for oncogene-induced DSBs has been provided by using the presence of p53 binding protein 1 (53BP1) nuclear foci as indicator of DSBs, whereby 10 20 foci per cell could be detected in cancer cell lines but not in proliferating normal cells [ 46].
Retinal sections from the 800 ng/eye dose group of the dose/response study (and the corresponding PBS control) were assessed for the thickness of the outer and inner nuclear layer as indicators of retinal health.
The technology could increase the power of existing reactors by 10percentt while extending the operating time between refuelings (a key economic indicator for nuclear plants) from 18 months to 24.
Because nuclear condensation is an indicator of apoptosis, a TUNEL assay was performed.
This nuclear accumulation is an indicator of a poor clinical outcome for breast cancer patients.
Lens transmission for blue light was measured with an ocular fluorometer (Fluorotron Master, OcuMetrics, Inc., Mountain View, CA) as an indicator of nuclear sclerosis and will be analyzed in a separate paper.
For some assays, cell viability was determined by counting the percentage of propidium iodide stained cells (1μg/mL) as counted under a fluorescence microscope in the presence of Hoescht 33342 nuclear counterstain as an indicator of the total cell number.
