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Cyclosporin is an immunosuppressant that reduces the nuclear expressions of HTLV-1Tax proteins of the leukemia cells making cyclosporin a useful agent for tumor treatment when combined with other anticancer agents (Ozaki et al. 2007).
Nuclear expressions of p16 and p21 in tumor cells were recognized as positive labels.
The median Q scores of cytoplasmic and nuclear expressions of p62 were 100 and 140, respectively.
Nuclear expressions of HIF-1 α and NF- κB/RelA were assessed in 251 human gastric carcinoma specimens by immunohistochemical tissue array analysis.
To our knowledge, this is the first study to investigate the cytoplasmic and nuclear expressions of this protein and their association to survival.
The relationship between cytoplasmic and nuclear expressions of p62 was modestly positively correlated in normal oral mucosas (rho=0.660) and verrucous hyperplasias (rho=0.566) but was negatively correlated in OSCCs (rho=−0.347).
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DSG significantly increased nuclear expression of ERβ.
The nuclear expression of LMP2, however, was more informative.
Co-localization of HDAC1 and UHRF2 was also revealed along with nuclear expression of all proteins.
Both factors induced the nuclear expression of PCNA in the mesenchimal cells around the bone trabeculae, and particularly BMP7 induced relatively large areas of osteoid material (Figure 4).
While basal nuclear expression of Nrf2 is hardly detected, a dramatic increase in nuclear expression of Nrf2 was observed in dh404-treated cells.
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