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On the other hand, as a result of the awareness of a tumor predisposition in NS among physicians, patients with NS and a malignancy are probably more likely to be referred for PTPN11 analysis than those with NS alone.
The detector works in free running mode with a dead time of 20 ns and a linear dynamic range of 36 dB.
In operation, the switches are controlled by four clock signals that have a period of 42 ns, and a frequency of 23.8 MHz.
Measurement results showed several useful features such as a recovery time of 8 ns and a gain of 1×106.
The TDC system operates with an input resolution of 1.2 ns, a minimum input pulse width of 4.8 ns and a minimum separation of 4.8 ns between pulses.
Post-layout simulation results showed a pulse width of 0.5 ns, and a peak-to-peak amplitude of 211 mV for one band spectrum.
Major design criteria are material budget, short shaping time in the order of 25 ns and a moderate spatial resolution of 80 μm.
The photodiode behaves a response time of 80 ns and a bandwidth of 14 MHz, which are higher than those of recent reports.
Each ASIC used in the design has 104 input channels with delay compensation circuitry providing steps of ∼3 ns and a full range of 25 ns for each channel.
Therefore, a LIBS system operating with a low energy NdCr YAG laser, a pulse energy of 3 mJ, a wavelength of 1064 nm, a pulse width of 1.5 ns and a repetition rate of 100 Hz has been used.
A light yield of 25 50 p.e./MIP, a time resolution of about 1 ns and a spatial resolution along the slab better than 10 cm were obtained for the SMRD counters.
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