In an EML4-ALK context, C1156Y was sensitive to all drugs, while in NPM-ALK it was slightly resistant to ASP3026 and ceritinib.
One of the first paid tools npm launched after it raised its seed round was npm Enterprise, a service that allows enterprises to run the package manager behind their firewalls and securely share their JavaScript modules for $20 per month and active user.
In npm's case, it even led to a production outage.
Today, npm announced that it has raised $8 million on top of the $2.6 million seed round led by True Ventures the company announced last February.
As npm notes on its jobs site, it doesn't want to be your typical "early-stage 'work hard/play hard' startup".
The NPM portion of NPM-ALK provides an oligomerization interface to permit dimerization of NPM-ALK monomers, followed by autophosphorylation and constitutive activation [17].
Schlueter tells me that being able to run a private registry has long been one of the most requested features from npm's users, but it took the company a while to launch this because running projects from multiple users on its own servers and being able to keep that data safe is a bit more difficult than the company's previous projects.
That might be more than you wanted to chew for haiku, but again, it's NPM and that's a great time to go beyond mere sampling.
Although it is easy to envision this as the "wet dream" of politicians, bureaucrats and NPM-proponents alike, it fails to meet the premise of the organizational code being a result of the cultural process of organizational learning.
However, equally important to the rise of Node.js has been the ecosystem that developed around it and its package manager, npm.
